2017 • Patient Partnership

Nikhil Wagle

NIKHIL WAGLE, a breast cancer oncologist and researcher at the Dana-Farber
Cancer Institute and Broad Institute, wanted to understand why some people with
metastatic breast cancer respond better to drugs than others, and why some have
more aggressive disease. He worked with patients to create the Metastatic Breast
Cancer Project, which collects and sequences DNA from patients’ tumors and
looks for genetic changes that are associated with how those patients responded,
or didn’t respond, to treatment. Wagle spoke with Xconomy about how working with
patients has changed how he thinks about research.

Nikhil Wagle of the Dana-Farber Cancer Institute and the Broad Institute • Photography by Alex Gagne and Rythum Vinoben