Tag Archives: Skyhawk Therapeutics

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Bio Roundup: FDA Dings BMS, Genfit’s Fall, Alexion’s Activist & More

This was a disappointing week for at least two major drug makers. French firm Genfit reported a trial failure in an intensely competitive indication, and New York-based Bristol Myers Squibb encountered a delay when the FDA declined to review its experimental multiple myeloma treatment. Genfit (NASDAQ: GNFT) was developing a treatment for nonalcoholic steatohepatitis, or […]

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Roche Pays $190M to Start RNA Drug Alliance With Arrakis Therapeutics

Some diseases have proven difficult to address using conventional tools of drug discovery that target disease-causing proteins. Roche is placing a $190 million bet on Arrakis Therapeutics, a startup whose technology aims for RNA—carriers of the genetic instructions that make these proteins in the first place. The cash, an upfront payment to Waltham, MA-based Arrakis, […]

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Bio Roundup: COVID-19 Trials, Esperion’s Approvals, NASH News & More

Clinical trials have historically hewn to a rigid format. A trial is designed, conducted according to that design, and then results are analyzed. Making changes in the midst of the study was a no-no. In recent years, regulators have showed openness to clinical trial designs intended to make drug testing more efficient. We’ll get to […]

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Bio Roundup: Opioid Exposé, Gilead’s Gambit, Life Science IPOs & More

The opioid crisis reaches all corners of the nation, and newly released data this week revealed how the growth of the epidemic tracked with a massive increase in the production and distribution of these drugs. From 2006 to 2012, the number of pills distributed to pharmacies increased by more than 50 percent. In total, 76 […]

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Skyhawk Inks Deal With Genentech for Cancer and Neuro Drug Discovery

Skyhawk Therapeutics has added Genentech to the growing list of companies it’s working with to find new drugs. The deal with Genentech, a Roche subsidiary, calls for Cambridge, MA-based Skyhawk to use its technology to discover and develop RNA-targeting drugs for cancer and neurological diseases. Under the deal announced Tuesday, Genentech receives an exclusive license […]

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Bio Roundup: Michael Becker, Suzanne Eaton, Gene Therapy Moves & More

The life science and healthcare worlds are vast. We often talk about impact in terms of millions of patients and billions of dollars. But these worlds can be small, too. It seems at times we’re never far removed from any one person, through their published papers, social media connections, friends, colleagues, or people they’ve mentored. […]

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The Finalists for the 2019 Xconomy Awards Are …

After a robust discussion, the editors and judges have narrowed down an impressive list of nearly 300 nominees for the 2019 Xconomy Awards in Boston to an all-star group of almost 60 finalists in 11 categories. Given the overall caliber of our nominees, we know it will be a tight race for the winners. Thankfully, we […]

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It’s Tough to Find Drugs to Bind to RNA: Arrakis Nabs $75M to Help

Arrakis Therapeutics has been scouting elusive pharmaceutical quarry: small molecules able to “drug” RNA, the molecular messengers that carry the genetic instructions for proteins. Most drugs in use today act on proteins. But CEO Michael Gilman says targeting the genetic blueprints could prevent RNA from translating those instructions into disease-causing proteins in the first place. […]

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Ribometrix Takes Aim at “Undruggable” RNA with $30M Series A Funding

Most drugs target proteins in the cell, but the world of RNA has remained largely untapped by companies making chemical-based, or small-molecule drugs. That’s changing though—just in the last couple of years, there’s been a mini-boom in biotechs trying to overturn the long-held dogma that messenger RNA molecules (which carry the genetic instructions for proteins […]

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The Winners of the 2018 Xconomy Awards Are…

This year’s nominees and finalists for the Xconomy Awards were even more impressive than last year’s (if that’s possible), making it that much tougher for our judges and the editors to pick the winners. There were multiple deserving winners in each category. But after much discussion and debate, we decided that these winners represent the […]

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