Tag Archives: pirfenidone

Pliant Pushes Forward With IPO Plans to Back Fibrosis Drug Studies

Pliant Therapeutics has a pipeline of experimental fibrosis treatments and a research alliance with Novartis. Now the biotech is preparing an IPO to raise cash to advance its clinical-stage programs. In paperwork filed with securities regulators, Pliant set an $86 million IPO target. That amount is a placeholder figure as the South San Francisco-based biotech […]

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Pliant Picks Up $62M to Test Lung, Liver Fibrosis Drug in the Clinic

The cause of fibrosis, the hardening and thickening of connective tissue in organs, isn’t known and it has few treatments. Pliant Therapeutics aims to bring patients who have this chronic and life-threatening condition in the lungs or the liver a new treatment option—and it now has $62 million to test its lead drug in humans. […]

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West Coast Biotech Roundup: Illumina, Atara, Invitae, Canaan & More

From big venture firms to tiny genomics startups, we’ve got plenty to round up this week—beyond biotech, too, as the San Francisco Giants head east to the biggest baseball rodeo for the third time in five years, thanks to Seattle native Travis Ishikawa (pictured). Here’s the windup, and the pitch… —Canaan Partners of Westport, CT, […]

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Genoa Pharma Aims To Satisfy Big Pharma’s Hunger for IPF Drugs

One of the hot areas of drug development these days can be filed under the header of “deadly lung scarring condition we don’t understand very well.” But the scientific knowledge of idiopathic pulmonary fibrosis is improving fast, and a new San Diego startup called Genoa Pharmaceuticals is betting it can satisfy Big Pharma’s hunger for […]

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InterMune Wins EU Approval

InterMune (NASDAQ: ITMN), the Brisbane, CA-based drug developer, said today that pirfenidone (Esbriet) has been cleared by regulators for sale in the 27 countries that make up the European Union. The drug will be marketed to treat mild to moderate idiopathic pulmonary fibrosis. InterMune says it plans to start commercializing the drug in September in […]

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Intermune Gets EU Advisory Nod; Shares Boom

Intermune (NASDAQ: ITMN), the Brisbane, CA-based maker of a drug for a deadly lung disease called pulmonary fibrosis, said today that it has won a positive recommendation for its treatment from a panel of expert advisors to European Union regulators. The Committee for Medicinal Products for Human Use of the European Medicines Agency recommended that […]

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Amira Pharmaceuticals’ Experimental Lung Disease Drug May Have Legs

The story around Amira Pharmaceuticals’ experimental drug AP2966 is beginning to get interesting. Yesterday the San Diego-based respiratory drug company said its experimental drug reduced lung scarring in mice, offering promise that the oral medication might one day be approved to treat pulmonary fibrosis. But it turns out there may be a lot more to this […]

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