For Those on Watch, Hope Springs Eternal as Hair Trials Inch Along

Xconomy San Diego — 

Waiting for the biotech industry to advance new treatments for male pattern baldness (as well as female hair loss) might seem about as exciting as watching hair grow. But some people have a lot of skin in the game, if you know what I mean.

More than just a few people, actually. San Diego’s Histogen estimates that hair loss affects some 40 million men and 21 million women in the United States alone. Histogen, which has been developing a bio-engineered treatment for stimulating hair growth, says less than 7 percent seek treatment for their hair loss “due to the limitations of available options.”

For these people, any incremental improvement in hair growth can be thrilling—even life-changing—which helps explain a burst of enthusiasm we’ve noticed in recent days in messages penned below a 2011 article about Boston-based Follica on the Xconomy Boston website. With close to 1,500 comments posted over the past 14 months our readers have shown no loss for words, making this one article a defacto online message board and a virtual support group for the follically challenged.

As I reported in 2010, few life sciences companies have gotten as much mileage from a pilot trial that enrolled two dozen patients as Histogen has for its much-anticipated treatment. The company says its formulation consists of proteins, including growth factor molecules, secreted by human fibroblast cells grown in a laboratory culture. The concoction is injected just below the scalp.

Over the past week, gentle and not so-gentle visitors to the Follica comment page have seized on the early results of Histogen’s latest experimental trial, which Histogen CEO Gail Naughton presented a week ago in Raleigh, NC, during the annual meeting of the Society for Investigative Dermatology. Naughton gave an oral summary of the data on May 11 and presented a poster the following day on “Stimulation of hair growth in humans by cell-secreted proteins.”

The data has not yet been published in a peer-reviewed scientific journal, according to a Histogen spokeswoman. “We are not releasing an announcement at this time,” she adds.

Yet Histogen has summarized its early findings on its website, where a PDF copy of the May 12 poster also can be downloaded. The company says 56 patients were enrolled in … Next Page »

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10 responses to “For Those on Watch, Hope Springs Eternal as Hair Trials Inch Along”

  1. McJ says:

    And who says Xconomy don’t pay attention to their Follica readers!? Sooo, what do Follica make of all this Histogen business? More to the point, what do Follica have to say for themselves? Still keeping mum as they say? You Xconomy guys keep asking right?

  2. Sjdfksd says:


  3. Herzog says:

    I’m glad we can move on from a Follica based thread to a Histogen based thread. We’ll see them patenting HSC in two years. Right on schedule to their projections back in 2010.
    This is the first time a company hasn’t re-upped its “in 5 years” projection. We’re actually making progress on a timeline.

    Wow. Carry on Histogen

  4. Guest says:

    Woohoo!  That means by the time my dotcom becomes profitable, I can re-grow my hair and marry a girl in her 20s.  I love the internet!

  5. julian says:

    Well said, Bruce Bigelow: “Waiting for the biotech industry to advance new treatments for male pattern baldness (as well as female hair loss) might seem about as exciting as watching hair grow.”

  6. Alex178 says:

    It seems that Bruce Bigelow succeed in killing this great forum.
    He must be proud some tried hard but Bruce did it.
    Very sad.

  7. rev says:


  8. Alex178 says:

    Finally it seems that some decided to ignore this new thread.
    Indeed the previous thread is starting again.

    I just hope hope that everyone will come back to share their discoveries.
    More people means more research on the web and more informations.

    • Alex178 says:

       By the old thread I mean “Follica Sheds More Light on Hair Re-Growth Invention”

  9. McJ says:

    Hey Bruce,

    I and some others on the other thread (ok, mostly me) do wonder if you good folks at Xconomy keep asking Follica for an update. So, you do ask right? Even a ‘nothing to report’ report would be kinda nice. At least so we know Follica are still active and such.

    Things are awfully quiet at the moment and we can’t help but wonder.

    Thanks for reading (assuming you actually read these)