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The 12 Days of Xconomists: Leading Innovators Give Their Top Advances of the Past Decade

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Top Five Biomedical Innovations of the 2000s (Bob More)
Highlight: “Novartis’ imatinib (Gleevec). The first drug for specifically inhibiting an enzyme causing cancer rather than killing fast dividing cells.”

Seven Computer Science Game-Changers from the 2000s (Ed Lazowska)
Highlight: “Today, you can search more than 500 Terabytes of the Web (not to mention your own desktop) in 100 milliseconds.”

The Top Five Advances From the Decade of Genomics (Clifford Reid)
Highlight: “Advanced diagnostics by blood biomarker analysis (e.g. fetal DNA/cells in mother’s blood).”

My Top 10 List of Innovations Across the Spectrum (Larry Bock)
Highlight: “High-tech treatment of nuclear waste, a technology that solves the key bottleneck to new nuclear growth and old nuclear cleanup.”

Top Five Tech Advances of the 2000s (Steve Hall)
Highlight: “The beginning of what will likely be a permanent shift to a world of digital media.” (Also, digital camera and camera phone proliferation.)

The Decade’s Most Important Biomedical Discovery (Phillip Sharp)
Highlight: “The most important discovery of the past decade is that of ‘induced pluripotent stem cells’ or ‘iPS cells,’ which are adult cells that have been coaxed back into a embryonic-stem-cell-like state.”

The Top Five Biotech Innovations of the 2000s (Clay Siegall)
Highlight: “Cancer therapies such as Roche/Genentech’s trastuzumab (Herceptin) and Celgene’s lenalidomide (Revlimid).”

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