Good Start Genetics Emerges from Stealth with $18M Series A Round

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jackpot with three really strong investors,” Hardison says.

Hardison joined Good Start as chief executive in April after a stint as chief operating officer of Laboratory Corp. of America, the Burlington, NC-based clinical test lab services giant. He says he was introduced to the company in January at the JP Morgan Healthcare Conference in San Francisco, where he met with the startup’s chairman Beer about taking the top job at the startup. Since he took the helm at the firm, he said, his big focus has been on closing the Series A round. (He noted that the startup has already paid back the loan it received from the Life Sciences Center last year.)

The startup’s four original founders remain involved in the firm, Hardison says. Paris Wallace and Eric Boutin, the Harvard MBAs, are executives of the firm, respectively. Greg Porreca, a former member of Church’s lab, is director of technology at the startup. Uri Laserson has remained in Church’s lab, yet he serves as a technical advisor to the firm.

Hardison highlighted some of the challenges that Good Start now faces, but he stressed that the company’s technological risk is low. The firm plans to use off-the-shelf genetic sequencing technology, initially from San Diego-based research tools and services provider Illumina (NASDAQ:ILMN). (He declined to discuss the details of the firm’s proprietary technology for capturing genetic information for its service.) A bigger challenge, however, will be breaking into the highly competitive market for pre-pregnancy genetic testing, according to the CEO.

Good Start plans to begin offering its sequencing-based tests through fertility clinics around the U.S., Hardison said. Doctors in such clinics already routinely order genetic tests for patients to help them find out if a patient is carrying genes for inherited disease such as cystic fibrosis, sickle cell anemia, and Tay-Sachs disease. He said the current genotyping and SNP-based tests that doctors typically order are not as comprehensive as gene sequencing. For example, he says that standard test for cystic fibrosis might only be able to show whether a patient has one of 23 mutations of the CF gene, while sequencing a patient’s genes enables doctors to learn whether they have any of the some 1,700 reported mutations of the gene that are linked to the disease.

The startup is now working on making sure that its sequencing service is in the same pricing ballpark as the existing tests. He noted that more than half the market, estimated at several hundred million dollars annually, is composed of patients who pay for the genetic tests out of pocket and without insurance reimbursements. Only a minority of states, including Massachusetts, provide insurance reimbursements for pre-pregnancy genetic tests. Key for the startup will be proving to doctors that its service provides more accurate results than existing tests at a price that is on par or lower than standard products.

Good Start appears to have impressed all the right people so far. Yet only time will tell whether the firm can win over doctors in fertility clinics, and couples who are looking for accurate genetic information before they make their decision on whether to have children.

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